The cost of a call and the cost of a put are almost directly related. If you have a $40 stock, a $40 call and a $40 put will be almost exactly the same price most of the time. If there is a difference, the possibility of an arbitrage usually exists meaning that there is a 0 risk strategy (minus commissions) to get something for nothing. This is true whether it’s a collar or another strategy. I don’t completely understand the full process that allows for that to happen, but a complex series of trades usually makes it possible. So if the price of a call and put are going to be the same that means generally the higher priced calls are due to greater risk. Some reasons may be historical volatility, as that plays a roll, but the implied volatility, that is, how much people expect or are betting on the stock to move, becomes important.
One covered call strategy is simply to seek the maximum yielding calls to sell. If you decide on this strategy, you probably want to check the recent put volume on this month’s contracts, and you also may want to make sure the company is solvent. It should have positive cash flow more current assets then current liabilities, and ideally increasing cash flow.
Often times biotech stocks will have negative cash flow because they have to spend money researching and eventually they hope to hit a major discovery. These stocks are very difficult to price as a discovery would make the company worth a lot, an approval 
of F.D.A. will also catapult the stock much higher. You also should look for some recent strength in the stock, and there should be no bearish chart patterns, that means no chart patterns as well as no sudden high volume sell offs recently and generally a stock that has had a sudden sharp drop is also a warning sign.
If you feel comfortable with selling these higher priced options, you want the sudden move that’s expected to be upward if at all. You are in a way betting that a move will not happen. Once you identify a target, I recommend selling slightly deeper in the money calls as this will cover you more in a decline. You will be collecting the theta, which is the cost of an options potential for gains that the option buyer must pay.
Maclin Vestor teaches about varioustrading systems and teaches you how to buy stock that works for you.
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