Can-Fite BioPharma Ltd. (NYSE MKT: CANF) (TASE:CFBI), a biotechnology company with a pipeline of proprietary small molecule drugs that address inflammatory, cancer and liver diseases, announced today that data from the interim analysis of Piclidenoson in its Phase III clinical study is expected to be released during Q4 2020. Moreover and in line with the reports that rheumatoid arthritis (RA) drugs have been introduced for the treatment of the Coronavirus, the Company is now exploring a collaboration to look at the effect of Piclidenoson against Coronavirus. Can Fite drug candidates possess anti-viral effect protected by a US patent US7589075.
Recently, two pharmaceutical companies announced the introduction of RA drugs for the treatment of patients with Coronavirus. Gilead is conducting a clinical study in China which combines its anti-viral drug candidate Remdisivir with the old RA drug chloroquine (http://www.natap.org/2020/newsUpdates/s41422-020-0282-0.pdf). In addition, Roche has donated its Actemra anti-RA drug for the treatment of patients in China (https://www.fiercepharma.com/pharma-asia/china-turns-roche-arthritis-drug-actemra-against-covid-19-new-treatment-guidelines?mkt_tok=eyJpIjoiTVdVeU5XUmpOMlUyWkRSaCIsInQiOiJxRUtpQjhUU2U5NkJGMkxlaEdiZDhoRVFTQkkxbjJzQUV6d1hacVV3T3gzNmRZN3R5d0JWd0ZBeXhQZUo5RTN1XC91QTFIemVBekpzNHdwaGFHZGo1TmYweVgzeUdudHc1Z0R4alFYaUYyMXpVeEN1WlVTa2dSVkhqZlkxbWpkT0oifQ%3D%3D&mrkid=685430).
Can Fite is now exploring the possibility to collaborate with leading virology labs to explore the anti-viral effect of its drugs against the Coronavirus based on the known anti-viral and anti-rheumatic effects of the company drugs.
Can Fite completed the enrolment of 50% of the 525 patients planned for its Phase III ACRobat™ trial to evaluate its drug candidate Piclidenoson as a first-line treatment for RA. An interim analysis is being implemented, and will be managed and monitored by an independent data monitoring committee (IDMC) that will have un-blinded access to the data which are expected during Q3 2020.
Source: Can-Fite BioPharma Ltd.
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