Just a handful of technologies deserve to be called “game changers”—and CRISPR-Cas9, the new gene-editing tool, is one of them. Discovered just three years ago, CRISPR is sweeping through labs around the world and researchers are already using it to experiment on diseases like cancer and AIDS, engineer new sources of clean energy, and create hardier plants and animals with the goal of wiping out world hunger. This Salon gathers bioengineers and medical researchers to take a hard look at the monumental changes hovering on the horizon.
The Big Ideas Series is supported in part by the John Templeton Foundation. Additional support provided by The Jackson Laboratory.
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Original Program Date: June 4, 2016
MODERATOR: Robert Benezra
PARTICIPANTS: Ellen Jorgensen, Ben Matthews, Neville Sanjana, Jacob S. Sherkow, Stephen Tsang
Robert Benezra Introduction 00:05
Participant Introductions 00:57
How was CRISPR discovered? 3:31
Is it surprising how quickly CRISPR has been embraced? 8:34
What are the significant ways scientists are using CRISPR? 12:25
Do we want to manipulate the human genome? 22:50
What are the ethics that come with CRISPR? 30:17
How would we release a gene drive into the world 35:22
The first retinal gene therapy trial 41:44
Can CRISPR be used to replace dopaminergic neurons? 49:07
As CRISPR becomes more available could it suffer from under or over regulation? 1:00:47
How much can CRISPR cost? 1:06:25
Will CRISPR be the breakthrough for treating disorders? 1:17:36